Self-Assembled Hyaluronic Acid Nanoparticles as a Potent Nanomedicine for Type 2 Diabetes

March 30, 2018

 

We are interested in research for the discovery of new target substances for thetreatment of diabetes.

Recently, we report that an self assembly Hyaluronic Acid Nanoparticles (HA-NP)  has therapeutic effects on Type 2 diabetes.

Treatment with HA-NPs in mice fed a high-fat diet suppressed macrophage infiltration into adipose tissue and activation of Nlrp3-ASC inflammasome, leading to reduced pro-inflammatory cytokines, normalized fasting blood glucose levels, and improved insulin sensitivity. These findings suggest that HA-NP could be a therapeutic agent for the treatment of type 2 diabetes

 

 

 

 

 

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The Laboratory of Molecular Biomedical Science.

 

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