Prof. Kim Wook
Full Professor
Department of Applied Chemistry and Biological Engineering
Ajou University
San 5 Woncheon-dong, Yeongtong-gu, Suwon, 443-749, Korea
Hyegang Hall 421
Tel: +82-31-219-2513
E-mail: wookkim21@ajou.ac.kr
About us.
We use self-assembled hyaluronic acid nanomedicine and peripheral CB1R antagonist for treating chronic inflammatory diseases.
also, we find out pathophysiological mechanisms and specific contrl methods to development of therapeutic intervention for inflammatory disease
Diabetes
Psoriasis
Inflammatory
bowel disease
LATEST RESEARCH
Although conventional topical approaches for treating psoriasis have been offered as an alternative, there are still unmet medical needs such as low skin-penetrating efficacy
and off-target adverse effects. A hyaluronic acid nanoparticle (HA-NP) formed by self-assembly of HA-hydrophobic moiety conjugates has been broadly studied as a nanocarrier for long-term and target-specific delivery of drugs....
Although osteoarthritis (OA) is the most prevalent degenerative joint disease, there is no effective disease- modifying therapy. We report an empty self-assembled hyaluronic acid nanoparticle (HA-NP) as a potential therapeutic agent for OA treatment. In mouse primary articular chondrocytes, HA-NPs blocked the receptor- mediated cellular uptake of free low-molecular-weight HA....
The Laboratory of Molecular Biomedical Science.